Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441498 | 0.89 | MCHR1 (0.56) | MAPTLMNAPOLBNPC1RAB9A | |
| SCHEMBL11194495 | 0.89 | EGFR (0.53) | MAPTLMNAPOLBNPC1RAB9A | |
| SCHEMBL11165965 | 0.89 | MCHR1 (0.55) | MAPTLMNAPOLBCNR1CXCR3 | |
| SCHEMBL10356773 | 0.89 | MCHR1 (0.55) | MAPTLMNAPOLBCNR1CXCR3 | |
| SCHEMBL11165531 | 0.89 | MCHR1 (0.55) | MAPTLMNAPOLBCNR1CXCR3 | |
| SCHEMBL11305498 | 0.87 | MAPT (0.53) | MAPTLMNANPC1RAB9ATP53 | |
| SCHEMBL11201219 | 0.87 | MAPT (0.48) | MAPTLMNAPOLBNPC1RAB9A | |
| SCHEMBL11178554 | 0.86 | MAPT (0.52) | MAPTLMNAPOLBNPC1RAB9A | |
| SCHEMBL11193056 | 0.86 | MAPT (0.46) | MAPTLMNAPOLBNPC1RAB9A | |
| SCHEMBL11191065 | 0.85 | MAPT (0.54) | MAPTLMNAPOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023569-B1 | DERIVATIVES OF CARBOXYLIC ACIDS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0023569-A1 | Derivatives of carboxylic acids, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | disclosed |