Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11193056 | 0.88 | MAPT (0.46) | MAPTLMNAMCHR1SMN1; SMN2TP53 | |
| SCHEMBL11182439 | 0.87 | LMNA (0.48) | MAPTLMNAMCHR1SMN1; SMN2TP53 | |
| SCHEMBL11191065 | 0.87 | MAPT (0.54) | MAPTLMNAMCHR1SMN1; SMN2TP53 | |
| SCHEMBL11197083 | 0.86 | MAPT (0.52) | MAPTLMNAMCHR1SMN1; SMN2TP53 | |
| SCHEMBL11441498 | 0.86 | MCHR1 (0.56) | MAPTLMNAMCHR1SMN1; SMN2NPC1 | |
| SCHEMBL11165965 | 0.85 | MCHR1 (0.55) | MAPTLMNAMCHR1CXCR3TSHR | |
| SCHEMBL10356773 | 0.85 | MCHR1 (0.55) | MAPTLMNAMCHR1CXCR3TSHR | |
| SCHEMBL11165531 | 0.85 | MCHR1 (0.55) | MAPTLMNAMCHR1CXCR3TSHR | |
| SCHEMBL11214411 | 0.85 | LMNA (0.43) | MAPTLMNAMCHR1NPC1RAB9A | |
| SCHEMBL11199855 | 0.85 | DNMT3A (0.48) | MAPTLMNAMCHR1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023569-B1 | DERIVATIVES OF CARBOXYLIC ACIDS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0023569-A1 | Derivatives of carboxylic acids, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | disclosed |