Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NAMPT | P43490 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197083 | 0.87 | MAPT (0.52) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11441498 | 0.86 | MCHR1 (0.56) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11165965 | 0.85 | MCHR1 (0.55) | MAPTLMNAMCHR1CYP2D6 | |
| SCHEMBL10356773 | 0.85 | MCHR1 (0.55) | MAPTLMNAMCHR1CYP2D6 | |
| SCHEMBL11165531 | 0.85 | MCHR1 (0.55) | MAPTLMNAMCHR1CYP2D6 | |
| SCHEMBL11194495 | 0.83 | EGFR (0.53) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11201219 | 0.83 | MAPT (0.48) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11178554 | 0.83 | MAPT (0.52) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11180080 | 0.83 | MAPT (0.54) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11193056 | 0.82 | MAPT (0.46) | MAPTLMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056144-A1 | Carboxylic acid derivatives, their preparation and use as pharmaceuticals | Dr. Karl Thomae GmbH (DE) | 1982-07-21 | — | — | EP | disclosed |