Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196148 | 0.91 | TSPO (0.40) | TSPOALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL11199117 | 0.83 | TSPO (0.42) | TSPOALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL11194130 | 0.83 | KMT2A (0.47) | — | |
| SCHEMBL11194360 | 0.82 | KMT2A (0.47) | — | |
| SCHEMBL11201159 | 0.80 | TSPO (0.40) | TSPOALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL11194217 | 0.78 | MAPT (0.37) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10979543 | 0.78 | ALDH1A1 (0.61) | ALDH1A1 | |
| SCHEMBL11199769 | 0.78 | EGFR (0.39) | TSPOALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL11205941 | 0.78 | TSPO (0.39) | TSPOALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL11199511 | 0.77 | CYP1A2 (0.44) | TSPOALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4397850-A | HYPOGLYCEMIC, ANTIDIABETIC | SANDOZ, INC. (US) | 1983-08-09 | — | — | US | disclosed |