Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | USP14 | P54578 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11198827 | 0.89 | PTGDR2 (0.43) | KMT2APOLBKDM4EPTGDR2LMNA | |
| SCHEMBL11194130 | 0.87 | KMT2A (0.47) | KMT2APOLBLMNA | |
| SCHEMBL11194360 | 0.86 | KMT2A (0.47) | KMT2APOLBKDM4ELMNA | |
| SCHEMBL11195809 | 0.85 | PTGDR2 (0.37) | KMT2APOLBKDM4EPTGDR2LMNA | |
| SCHEMBL11201252 | 0.85 | PTGDR2 (0.39) | KMT2APOLBKDM4EPTGDR2NPC1 | |
| SCHEMBL10977892 | 0.80 | POLB (0.43) | KMT2APOLBKDM4ELMNAALDH1A1 | |
| SCHEMBL11202391 | 0.76 | MAPT (0.36) | KMT2APOLBKDM4EPTGDR2LMNA | |
| SCHEMBL11194217 | 0.75 | MAPT (0.37) | KDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11197970 | 0.73 | PTGDR2 (0.35) | KMT2APOLBPTGDR2NPC1RAB9A | |
| SCHEMBL11205806 | 0.73 | PTGDR2 (0.46) | KMT2APTGDR2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4397850-A | HYPOGLYCEMIC, ANTIDIABETIC | SANDOZ, INC. (US) | 1983-08-09 | — | — | US | disclosed |