SCHEMBL11201252

SCHEMBL11201252

CCc1noc(C)c1-c1c(C(=O)C(=O)N(C)C)c2cc(F)ccc2n1C

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.39
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM4E B2RXH2 1/20 0.34
SRC P12931 1/20 0.33
ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11194217 0.90 MAPT (0.37) KDM4E
SCHEMBL11205806 0.88 PTGDR2 (0.46) PTGDR2KMT2ASRC
SCHEMBL11197658 0.87 ALDH1A1 (0.41) RAB9ANPC1POLBKMT2AKDM4E
SCHEMBL11196148 0.86 TSPO (0.40) RAB9ANPC1SRC
SCHEMBL11197697 0.85 KMT2A (0.43) PTGDR2RAB9ANPC1POLBKMT2A
SCHEMBL11199117 0.79 TSPO (0.42) RAB9ANPC1SRC
SCHEMBL10977643 0.78 NPC1 (0.38) RAB9ANPC1
SCHEMBL11197970 0.78 PTGDR2 (0.35) PTGDR2RAB9ANPC1POLBKMT2A
SCHEMBL11197151 0.77 TSPO (0.44) RAB9ANPC1
SCHEMBL11201159 0.76 TSPO (0.40) RAB9ANPC1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4397850-A HYPOGLYCEMIC, ANTIDIABETIC SANDOZ, INC. (US) 1983-08-09 US disclosed