SCHEMBL11197836

SCHEMBL11197836

O=C(O)c1cc(OC(=O)c2ccccc2C(=O)O)ccc1OC(=O)c1ccccc1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.54
HSD17B10 Q99714 7/20 0.54
ALDH1A1 P00352 7/20 0.54
HPGD P15428 6/20 0.54
LMNA P02545 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C9 P11712 1/20 0.53
ALOX15 P16050 2/20 0.47
TSHR P16473 2/20 0.47
KMT2A Q03164 2/20 0.47
TDP1 Q9NUW8 3/20 0.46
PTGS2 P35354 2/20 0.46
ESR1 P03372 1/20 0.46
ITGB3 P05106 1/20 0.46
ITGA2B P08514 1/20 0.46
HMGB1 P09429 1/20 0.46
GGT1 P19440 1/20 0.46
PTGS1 P23219 1/20 0.46
BLM P54132 1/20 0.46
NAPRT Q6XQN6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11284057 0.88 ALDH1A1 (0.58) KDM4EHSD17B10ALDH1A1HPGDLMNA
SCHEMBL29204714 0.88 ALDH1A1 (0.58) KDM4EHSD17B10ALDH1A1HPGDLMNA
SCHEMBL11194444 0.87 KDM4E (0.58) KDM4EHSD17B10ALDH1A1HPGDLMNA
SCHEMBL10783424 0.84 HSD17B10 (0.62) KDM4EHSD17B10ALDH1A1HPGDLMNA
SCHEMBL11278084 0.83 KDM4E (0.54) KDM4EHSD17B10ALDH1A1HPGDLMNA
SCHEMBL10782155 0.82 MAPT (0.58) KDM4EHSD17B10ALDH1A1HPGDLMNA
SCHEMBL8582058 0.80 KDM4E (0.75) KDM4EHSD17B10ALDH1A1HPGDLMNA
SCHEMBL11191978 0.80 MAPT (0.56) KDM4EALDH1A1KMT2ATDP1ESR1
SCHEMBL11208120 0.80 KDM4E (0.79) KDM4EHSD17B10ALDH1A1HPGDLMNA
SCHEMBL251479 0.80 HSD17B10 (0.68) KDM4EHSD17B10ALDH1A1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4390683-A Stretched film structure of the poly-1,3-phenylene terephthalate type MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1983-06-28 US disclosed
EP-0052927-A2 Stretched film structure of the poly-1,3-phenylene terephthalate type MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-06-02 EP disclosed