Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380990 | 0.85 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2CYP3A4TDP1MAPT | |
| SCHEMBL31634600 | 0.85 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2CYP3A4TDP1MAPT | |
| SCHEMBL7375508 | 0.76 | MAPT (0.44) | ALDH1A1SMN1; SMN2CYP3A4TDP1MAPT | |
| SCHEMBL11205027 | 0.76 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2CYP3A4TDP1MAPT | |
| SCHEMBL11105087 | 0.76 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2CYP3A4TDP1MAPT | |
| SCHEMBL11107230 | 0.76 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2CYP3A4TDP1MAPT | |
| SCHEMBL11105091 | 0.76 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2CYP3A4TDP1MAPT | |
| SCHEMBL11198397 | 0.74 | ESR1 (0.45) | ALDH1A1SMN1; SMN2CYP3A4TDP1LMNA | |
| SCHEMBL11353384 | 0.73 | TSHR (0.44) | ALDH1A1SMN1; SMN2MAPTLMNAAPAF1 | |
| SCHEMBL7383445 | 0.71 | CYP3A4 (0.42) | ALDH1A1SMN1; SMN2CYP3A4TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086438-A1 | Process and intermediates for preparing 4-hydroxymethyl-1-phthalazone derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1983-08-24 | — | — | EP | claimed |
| EP-0086438-A1 | Process and intermediates for preparing 4-hydroxymethyl-1-phthalazone derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1983-08-24 | — | — | EP | disclosed |