Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11405234 | 0.85 | HTT (0.47) | MAPTALDH1A1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL7380990 | 0.82 | ALDH1A1 (0.47) | MAPTALDH1A1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL31634600 | 0.82 | ALDH1A1 (0.47) | MAPTALDH1A1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL11198525 | 0.76 | ALDH1A1 (0.42) | MAPTALDH1A1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL11205027 | 0.73 | ALDH1A1 (0.40) | MAPTALDH1A1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL11107230 | 0.73 | ALDH1A1 (0.39) | MAPTALDH1A1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL11105091 | 0.73 | ALDH1A1 (0.39) | MAPTALDH1A1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL11105087 | 0.73 | ALDH1A1 (0.39) | MAPTALDH1A1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL11198397 | 0.71 | ESR1 (0.45) | ALDH1A1CYP3A4SMN1; SMN2TDP1LMNA | |
| SCHEMBL11406347 | 0.70 | KDM4E (0.46) | MAPTALDH1A1CYP3A4HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4293553-A | ANTITHROMBOTIC AGENT | Ishikawa, Masayuki (JP) | 1981-10-06 | — | — | US | disclosed |
| US-3963716-A | HYPOTENSIVE, TREATMENT OF THROBOSIS, ANTHROSCLLEROSIS | SHIMAMOTO, TAKIO (JP) | 1976-06-15 | — | — | US | disclosed |