Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 5/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.56 |
| ▸ | QPCT | Q16769 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11165829 | 0.91 | DRD2 (0.62) | ALDH1A1USP2LMNAMAPTHPGD | |
| SCHEMBL11173613 | 0.90 | MCHR1 (0.66) | ALDH1A1USP2LMNAMAPTHPGD | |
| SCHEMBL11176687 | 0.89 | MCHR1 (0.60) | ALDH1A1USP2LMNAMAPTHPGD | |
| SCHEMBL11172284 | 0.88 | ALDH1A1 (0.55) | ALDH1A1USP2LMNAMAPTHPGD | |
| SCHEMBL11160725 | 0.88 | ALDH1A1 (0.55) | ALDH1A1USP2LMNAMAPTHPGD | |
| SCHEMBL11169527 | 0.88 | DRD2 (0.58) | ALDH1A1USP2LMNAMAPTHPGD | |
| SCHEMBL11168230 | 0.87 | MAPT (0.55) | ALDH1A1USP2LMNAMAPTHPGD | |
| SCHEMBL11167746 | 0.87 | MAPT (0.55) | ALDH1A1USP2LMNAMAPTHPGD | |
| SCHEMBL11159508 | 0.87 | MAPT (0.55) | ALDH1A1USP2LMNAMAPTHPGD | |
| SCHEMBL11169258 | 0.87 | DRD2 (0.57) | ALDH1A1USP2LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4413006-A | N-Aryl-N-phenoxy-alkyl-piperazine compounds useful in decreasing intracranial pressure | TANABE SEIYAKU CO., LTD. (JP) | 1983-11-01 | — | — | US | disclosed |
| EP-0034284-B1 | PIPERAZINE DERIVATIVE, PROCESSES FOR PREPARING THE SAME AND THERAPEUTIC COMPOSITIONS CONTAINING IT | Tanabe Seiyaku Co., Ltd. (JP) | 1983-10-05 | — | — | EP | disclosed |
| EP-0034284-A2 | Piperazine derivative, processes for preparing the same and therapeutic compositions containing it | Tanabe Seiyaku Co., Ltd. (JP) | 1981-08-26 | — | — | EP | disclosed |