Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.51 |
| ▸ | CFTR | P13569 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | MDH2 | P40926 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL11140359 | 0.93 | PTPN22 (0.60) | PTPN22CFTRHPGDCYP1A2GABRA1 | |
| SCHEMBL11143397 | 0.89 | PTPN22 (0.60) | PTPN22CFTRALDH1A1HPGDMEN1 | |
| Imidazole SCHEMBL11187764 | 0.85 | PTPN22 (0.40) | PTPN22CFTRALDH1A1HPGDMEN1 | |
| SCHEMBL11144705 | 0.81 | PTPN22 (0.71) | PTPN22CFTRHPGDCYP1A2 | |
| Imidazole SCHEMBL11136643 | 0.80 | KDM4E (0.41) | PTPN22CFTRALDH1A1HPGDCYP1A2 | |
| Imidazole SCHEMBL11187054 | 0.79 | ALDH1A1 (0.40) | PTPN22ALDH1A1HPGDCYP1A2MAOA | |
| SCHEMBL11142165 | 0.79 | PTPN22 (0.43) | PTPN22CFTRGABRA1GABRB1GABRA5 | |
| SCHEMBL16112737 | 0.76 | ALDH1A1 (0.56) | CFTRALDH1A1HPGDMEN1CYP1A2 | |
| Imidazole SCHEMBL11144695 | 0.75 | HPGDS (0.45) | CFTRALDH1A1HPGDMEN1CYP1A2 | |
| Imidazole SCHEMBL11204563 | 0.73 | HTT (0.44) | PTPN22CFTRHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4404201-A | N-/ /ALKANOYLAMINOALKANOYLAMINO OR AMINOALKANOYL AMINO/-DIHYDRO-OXO-3-QUINOLINYLCARBONYL/- DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1983-09-13 | — | — | US | disclosed |