Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3011286 | 0.73 | KDM4E (0.41) | KDM4EMAPTCYP3A4ALOX15HPGD | |
| SCHEMBL246438 | 0.72 | KDM4E (0.53) | KDM4EMAPTCYP3A4ALOX15HPGD | |
| SCHEMBL19689360 | 0.70 | HTR2A (0.40) | CYP3A4TDP1LMNASLC6A2SLC6A4 | |
| SCHEMBL28639731 | 0.70 | KDM4E (0.52) | KDM4EMAPTCYP3A4ALOX15HPGD | |
| Ammonia Solution, Strong SCHEMBL27626967 | 0.70 | KDM4E (0.52) | KDM4EMAPTCYP3A4ALOX15HPGD | |
| SCHEMBL28307922 | 0.69 | CFTR (0.57) | KDM4EMAPTCYP3A4ALOX15ALDH1A1 | |
| SCHEMBL7640862 | 0.67 | KDM4E (0.39) | KDM4EMAPTCYP3A4ALOX15HPGD | |
| SCHEMBL28278739 | 0.66 | KDM4E (0.44) | KDM4EMAPTCYP3A4ALOX15HPGD | |
| SCHEMBL10569701 | 0.66 | SLC6A2 (0.57) | KDM4EMAPTCYP3A4ALOX15HPGD | |
| SCHEMBL29029215 | 0.66 | SLC6A2 (0.57) | KDM4EMAPTCYP3A4ALOX15HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022634-B1 | ACYLATED INDOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS AND DRUGS COMPRISING THEM | TEIJIN LIMITED (JP) | 1983-04-06 | — | — | EP | disclosed |