SCHEMBL7640862

SCHEMBL7640862

C=CC(c1ccccc1)c1cccnn1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.39
MAPT P10636 4/20 0.39
CYP3A4 P08684 3/20 0.39
ALOX15 P16050 3/20 0.39
SLC6A2 P23975 3/20 0.36
SLC6A4 P31645 3/20 0.36
SLC6A3 Q01959 3/20 0.36
HPGD P15428 3/20 0.35
USP2 O75604 2/20 0.35
TP53 P04637 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
LMNA P02545 1/20 0.35
ALOX12 P18054 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
KMT2A Q03164 1/20 0.35
SLC6A9 P48067 1/20 0.34
CFTR P13569 1/20 0.32
GOPC Q9HD26 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29029215 0.78 SLC6A2 (0.57) KDM4EMAPTCYP3A4ALOX15SLC6A2
SCHEMBL10569701 0.78 SLC6A2 (0.57) KDM4EMAPTCYP3A4ALOX15SLC6A2
Hydrochloric Acid SCHEMBL28453921 0.76 SLC6A2 (0.55) KDM4EMAPTCYP3A4ALOX15SLC6A2
Ammonia Solution, Strong SCHEMBL6000289 0.76 SLC6A2 (0.55) KDM4EMAPTCYP3A4ALOX15SLC6A2
SCHEMBL246438 0.73 KDM4E (0.53) KDM4EMAPTCYP3A4ALOX15HPGD
SCHEMBL29097523 0.72 SLC6A2 (0.39) SLC6A2SLC6A4SLC6A3ALDH1A1SLC6A9
SCHEMBL2007587 0.72 SLC6A2 (0.39) SLC6A2SLC6A4SLC6A3SLC6A9CFTR
SCHEMBL28509590 0.72 SLC6A2 (0.39) KDM4ESLC6A2SLC6A4SLC6A3HPGD
SCHEMBL27085226 0.72 SMN1; SMN2 (0.50) KDM4ESLC6A2SLC6A4SLC6A3HPGD
SCHEMBL11395884 0.72 GOT1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11325991-B2 All-acrylic multigraft copolymer superelastomers UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2022-05-10 US disclosed
US-20210108018-A1 ALL-ACRYLIC MULTIGRAFT COPOLYMER SUPERELASTOMERS UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2021-04-15 US disclosed
WO-2018200671-A1 ALL-ACRYLIC MULTIGRAFT COPOLYMER SUPERELASTOMERS UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2018-11-01 WO disclosed
EP-0764506-B1 PROCESS FOR PRODUCING MULTI-LAYER MOLDED ARTICLES ARACO KK (JP) 2002-01-02 EP disclosed
US-5961902-A Manufacturing method for molded multilayer article ARACO KABUSHIKI KAISHA (JP) 1999-10-05 US disclosed
EP-0764506-A1 PROCESS FOR PRODUCING MULTI-LAYER MOLDED ARTICLES ARACO KABUSHIKI KAISHA (JP) 1997-03-26 EP disclosed