Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA2 | P00918 | 4/20 | 0.32 |
| ▸ | CA9 | Q16790 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1041306 | 0.87 | THRB (0.41) | TSHRTHRBMAPTCA1CA2 | |
| SCHEMBL17644810 | 0.85 | ADRB2 (0.41) | TSHRTHRBMAPTNR5A1CA1 | |
| SCHEMBL11572901 | 0.85 | THRB (0.47) | TSHRTHRBMAPTCA1CA2 | |
| SCHEMBL766409 | 0.85 | THRB (0.47) | TSHRTHRBMAPTCA1CA2 | |
| SCHEMBL77168 | 0.85 | THRB (0.47) | TSHRTHRBMAPTCA1CA2 | |
| SCHEMBL11592491 | 0.85 | THRB (0.47) | TSHRTHRBMAPTCA1CA2 | |
| SCHEMBL2397962 | 0.85 | THRB (0.47) | TSHRTHRBMAPTCA1CA2 | |
| SCHEMBL17644807 | 0.85 | ADRB2 (0.41) | TSHRTHRBMAPTNR5A1CA1 | |
| SCHEMBL7172026 | 0.85 | THRB (0.47) | TSHRTHRBMAPTCA1CA2 | |
| SCHEMBL9119727 | 0.85 | THRB (0.47) | TSHRTHRBMAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4390712-A | Aqueous solution of cationic organosilicon compounds and process for the production of the solutions | DEGUSSA AG (DE) | 1983-06-28 | — | — | US | disclosed |