Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197858 | 0.90 | POLB (0.43) | POLBGAARAB9AFFAR2HSD17B10 | |
| SCHEMBL11199586 | 0.89 | POLB (0.50) | POLBGAARAB9AFFAR2HSD17B10 | |
| SCHEMBL11198036 | 0.84 | HTR7 (0.38) | POLBFFAR2HSD17B10ACE | |
| SCHEMBL11197149 | 0.84 | HTR7 (0.38) | POLBFFAR2HSD17B10ACE | |
| SCHEMBL11195847 | 0.83 | CNR1 (0.39) | POLBFFAR2HSD17B10ACE | |
| SCHEMBL11199535 | 0.76 | ACE (0.41) | ACE | |
| SCHEMBL11110245 | 0.75 | HSD17B10 (0.48) | POLBGAARAB9AFFAR2HSD17B10 | |
| SCHEMBL11068375 | 0.74 | POLB (0.44) | POLBGAARAB9AFFAR2HSD17B10 | |
| SCHEMBL11202090 | 0.72 | ACE (0.45) | ACE | |
| SCHEMBL11190975 | 0.72 | ACE (0.45) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4374249-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-02-15 | — | — | US | disclosed |