Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | FFAR2 | O15552 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068375 | 0.94 | POLB (0.44) | HSD17B10FFAR2POLBGAARAB9A | |
| SCHEMBL11248466 | 0.93 | FFAR2 (0.44) | HSD17B10FFAR2POLBGAARAB9A | |
| SCHEMBL11234757 | 0.90 | KDM4E (0.41) | HSD17B10FFAR2ALDH1A1 | |
| SCHEMBL11066449 | 0.89 | HTT (0.44) | HSD17B10FFAR2POLBGAARAB9A | |
| SCHEMBL11062261 | 0.87 | ACE (0.56) | FFAR2POLBALDH1A1HTTACE | |
| SCHEMBL11169752 | 0.86 | HTT (0.38) | HSD17B10FFAR2POLBGAARAB9A | |
| SCHEMBL11065215 | 0.86 | HTT (0.38) | HSD17B10FFAR2POLBGAARAB9A | |
| SCHEMBL11184480 | 0.85 | FFAR2 (0.52) | HSD17B10FFAR2POLBGAARAB9A | |
| SCHEMBL11181660 | 0.83 | FFAR2 (0.35) | FFAR2HTTACE | |
| SCHEMBL11104269 | 0.82 | LMNA (0.46) | FFAR2POLBMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4457935-A | ANGIOTENSIN-CONVERTING ENZYME INHIBITOR | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-07-03 | — | — | US | claimed |