Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8390401 | 0.74 | MAPT (0.41) | MAPTKDM4EALDH1A1GAACASP1 | |
| SCHEMBL18641994 | 0.72 | APP (0.53) | MAPTKDM4EALDH1A1GAAKIF11 | |
| SCHEMBL11195362 | 0.71 | TDP1 (0.54) | MAPTKDM4EALDH1A1GAACASP1 | |
| SCHEMBL11193071 | 0.71 | MAPT (0.46) | MAPTKDM4EALDH1A1GAACASP1 | |
| SCHEMBL30443913 | 0.68 | GRIN2D (0.59) | MAPTKDM4EALDH1A1GAACASP1 | |
| SCHEMBL5684603 | 0.68 | GRIN2D (0.59) | MAPTKDM4EALDH1A1GAACASP1 | |
| SCHEMBL8390363 | 0.68 | MAPT (0.47) | MAPTKDM4EALDH1A1GAACASP1 | |
| Terephthalic Acid SCHEMBL29145313 | 0.68 | KIF11 (0.46) | MAPTKDM4EALDH1A1GAAKIF11 | |
| SCHEMBL8389032 | 0.68 | PPARG (0.42) | MAPTKDM4EALDH1A1GAACASP1 | |
| SCHEMBL4535317 | 0.68 | MAPT (0.62) | MAPTKDM4EALDH1A1GAACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068563-A2 | Heterocyclic acetic acid compounds and compositions for treating bone diseases | THE PROCTER & GAMBLE COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |