Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | PRKCI | P41743 | 8/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203744 | 0.99 | HTR2C (0.55) | HTR2CDRD2PRKCIPRKCZADRB1 | |
| SCHEMBL11200556 | 0.97 | HTR2C (0.53) | HTR2CDRD2PRKCIPRKCZADRB1 | |
| SCHEMBL11204214 | 0.88 | KDM4E (0.53) | HTR2CDRD2PRKCIPRKCZMAPT | |
| SCHEMBL11206910 | 0.87 | KDM4E (0.52) | HTR2CDRD2PRKCIPRKCZMAPT | |
| SCHEMBL11202996 | 0.86 | KDM4E (0.43) | HTR2CMAPTKDM4EUSP2ALDH1A1 | |
| SCHEMBL11202830 | 0.86 | MEN1 (0.58) | PRKCIPRKCZMAPTKDM4EUSP2 | |
| SCHEMBL11207162 | 0.86 | KDM4E (0.55) | HTR2CDRD2PRKCIPRKCZMAPT | |
| Hydrochloric Acid SCHEMBL11200717 | 0.85 | MEN1 (0.57) | PRKCIPRKCZMAPTKDM4EUSP2 | |
| SCHEMBL11200838 | 0.85 | ALDH1A1 (0.43) | MAPTKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL11198472 | 0.84 | ALDH1A1 (0.60) | HTR2CDRD2PRKCIPRKCZMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |