Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | PRKCI | P41743 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11204214 | 0.98 | KDM4E (0.53) | KDM4EALDH1A1HTR2CPRKCZALOX15 | |
| SCHEMBL11206910 | 0.97 | KDM4E (0.52) | KDM4EALDH1A1HTR2CPRKCZALOX15 | |
| SCHEMBL11200556 | 0.88 | HTR2C (0.53) | KDM4EALDH1A1HTR2CPRKCZDRD2 | |
| SCHEMBL11200702 | 0.87 | ALDH1A1 (0.57) | KDM4EALDH1A1HTR2CPRKCZALOX15 | |
| SCHEMBL11199834 | 0.86 | HTR2C (0.56) | KDM4EALDH1A1HTR2CPRKCZALOX15 | |
| SCHEMBL11203744 | 0.85 | HTR2C (0.55) | KDM4EALDH1A1HTR2CPRKCZALOX15 | |
| SCHEMBL11198472 | 0.84 | ALDH1A1 (0.60) | KDM4EALDH1A1HTR2CPRKCZALOX15 | |
| Hydrochloric Acid SCHEMBL11200060 | 0.84 | ALDH1A1 (0.59) | KDM4EALDH1A1HTR2CPRKCZALOX15 | |
| SCHEMBL11201180 | 0.84 | ALDH1A1 (0.59) | KDM4EALDH1A1HTR2CPRKCZALOX15 | |
| SCHEMBL11204226 | 0.81 | ALDH1A1 (0.50) | KDM4EALDH1A1ALOX15USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |