Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | ERN1 | O75460 | 8/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3631682 | 0.82 | ERN1 (0.46) | MCL1ERN1TLR2TLR1TLR6 | |
| SCHEMBL24542205 | 0.78 | ERN1 (0.50) | MCL1ERN1TLR2TLR1TLR6 | |
| SCHEMBL21822829 | 0.78 | ERN1 (0.39) | MCL1ERN1TLR2TLR1TLR6 | |
| SCHEMBL17377670 | 0.77 | ERN1 (0.45) | ERN1TLR2TLR1TLR6PTGES | |
| SCHEMBL1832013 | 0.74 | ERN1 (0.46) | ERN1TLR2TLR1TLR6MAPT | |
| SCHEMBL2477378 | 0.73 | TLR2 (0.56) | ERN1TLR2TLR1TLR6ALOX5 | |
| SCHEMBL11201117 | 0.72 | MEN1 (0.39) | ERN1TLR2TLR1TLR6PTGES | |
| SCHEMBL6244440 | 0.71 | ALDH1A1 (0.41) | MCL1MAPTMEN1CYP1A2TSHR | |
| SCHEMBL7819137 | 0.71 | SLC2A1 (0.45) | MEN1CYP1A2TSHRKMT2AALDH1A1 | |
| SCHEMBL696593 | 0.70 | BACE1 (0.47) | ERN1ALOX5MAPTHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080419-A2 | 8-Haloalkyl-4H-(1)-benzopyran-4-ones and preparation processes | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1983-06-01 | — | — | EP | disclosed |