Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.38 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24542205 | 0.87 | ERN1 (0.50) | ERN1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL3631682 | 0.84 | ERN1 (0.46) | ERN1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL21822829 | 0.80 | ERN1 (0.39) | ERN1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL9519002 | 0.79 | PDE4A (0.42) | ERN1MEN1KMT2AMAPTTSHR | |
| SCHEMBL24541830 | 0.78 | CA1 (0.40) | ERN1MEN1KMT2ACYP1A2TSHR | |
| SCHEMBL9518445 | 0.77 | IDO1 (0.41) | ERN1MEN1KMT2AMAPTTSHR | |
| SCHEMBL1829471 | 0.77 | ERN1 (0.34) | ERN1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL2477378 | 0.76 | TLR2 (0.56) | ERN1MAPTHSD17B10ALDH1A1TLR2 | |
| SCHEMBL11199853 | 0.74 | MCL1 (0.42) | ERN1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL5069879 | 0.74 | ERN1 (0.58) | ERN1ALDH1A1TLR2TLR1TLR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318375-A1 | IMIDAZOLE CARBOXAMIDES | ELI LILLY AND COMPANY (US) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010009062-A1 | IMIDAZOLE CARBOXAMIDES | ELI LILLY AND COMPANY (US) | 2010-01-21 | — | — | WO | disclosed |