Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 8/20 | 0.56 |
| ▸ | CES1 | P23141 | 7/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrous Acid SCHEMBL27814127 | 0.92 | CES2 (0.48) | CES2CES1AKR1C1NFE2L2ALDH1A1 | |
| SCHEMBL164580 | 0.84 | AKR1C1 (0.59) | CES2CES1AKR1C1NFE2L2ALDH1A1 | |
| SCHEMBL165294 | 0.84 | AKR1C1 (0.59) | CES2CES1AKR1C1NFE2L2ALDH1A1 | |
| SCHEMBL164579 | 0.84 | AKR1C1 (0.59) | CES2CES1AKR1C1NFE2L2ALDH1A1 | |
| SCHEMBL210320 | 0.83 | AKR1C1 (0.44) | CES2CES1AKR1C1NFE2L2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3674640 | 0.82 | AKR1C1 (0.57) | CES2CES1AKR1C1NFE2L2ALDH1A1 | |
| SCHEMBL728125 | 0.80 | TSHR (0.50) | CES2CES1TSHRRAB9A | |
| SCHEMBL8764232 | 0.80 | CYP2C19 (0.50) | CES2CES1AKR1C1NFE2L2ALDH1A1 | |
| SCHEMBL4651337 | 0.80 | CES2 (0.52) | CES2CES1AKR1C1NFE2L2ALDH1A1 | |
| SCHEMBL5273984 | 0.80 | AKR1C1 (0.45) | CES2CES1AKR1C1NFE2L2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12128257-B2 | Extracts of Isochrysis sp | SYMRISE AG (DE) | 2024-10-29 | — | — | US | disclosed |
| US-20240335364-A1 | COMPOSITIONS OF DICAFFEOYLQUINIC ACIDS WITH TOCOPHEROL | SYMRISE AG (DE) | 2024-10-10 | — | — | US | disclosed |
| EP-4442241-A2 | RETINOL REPLACEMENT IN SKIN TREATMENT | Symrise AG (DE) | 2024-10-09 | — | — | EP | disclosed |
| EP-3615147-B1 | YARROW FRESH-PLANT PRESSED JUICE CONCENTRATE, PRODUCTION, AND USE | SYMRISE AG (DE) | 2024-09-11 | — | — | EP | disclosed |
| EP-3773445-B1 | RETINOL REPLACEMENT IN SKIN TREATMENT | SYMRISE AG (DE) | 2024-07-24 | — | — | EP | disclosed |
| EP-4373462-A1 | COMPOSITIONS OF DICAFFEOYLQUINIC ACIDS WITH TOCOPHEROL | Symrise AG (DE) | 2024-05-29 | — | — | EP | disclosed |
| US-20240130957-A1 | EXTRACTS OF ISOCHRYSIS SPECIES/TISOCHRYSIS SPECIES | SYMRISE AG (DE) | 2024-04-25 | — | — | US | disclosed |
| CN-117651544-A | Synergistic effect of dicaffeoylquinic acid and tocopherol | 西姆莱斯有限公司 | 2024-03-05 | — | — | CN | disclosed |
| US-11801210-B2 | Retinol replacement in skin treatment | SYMRISE AG (DE) | 2023-10-31 | — | — | US | disclosed |
| EP-4259090-A1 | EXTRACTS OF ISOCHRYSIS SPECIES / TISOCHRYSIS SPECIES | Symrise AG (DE) | 2023-10-18 | — | — | EP | disclosed |
| WO-2010089421-A2 | MENTHYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS | SYMRISE GMBH & CO. KG (DE) | 2010-08-12 | — | — | WO | disclosed |
| WO-2010070152-A2 | USE OF DIHYDRODEHYDRODIISOEUGENOL AND PREPARATIONS COMPRISING DIHYDRODEHYDRODIISOEUGENOL | SYMRISE GMBH & CO. KG (DE) | 2010-06-24 | — | — | WO | disclosed |
| US-20100143267-A1 | EXTRACTS OF TETRASELMIS SP. | SYMRISE GMBH & CO. KG (DE) | 2010-06-10 | — | — | US | disclosed |
| EP-2193785-A2 | Extracts of Tetraselmis sp. for cosmetic and therapeutic purposes | Symrise GmbH & Co. KG (DE) | 2010-06-09 | — | — | EP | disclosed |
| US-20100080761-A1 | Extracts of Isochrysis sp. | SYMRISE GMBH & CO. KG (DE) | 2010-04-01 | — | — | US | disclosed |
| EP-2168570-A2 | Extracts of isochrysis sp. | Symrise GmbH & Co. KG (DE) | 2010-03-31 | — | — | EP | disclosed |
| WO-2010000877-A2 | FORMULATION WITH IRRITATION REDUCING ACTION COMPRISING BISABOLOL AND [6]-PARADOL | SYMRISE GMBH & CO. KG (DE) | 2010-01-07 | — | — | WO | disclosed |
| WO-2009101216-A2 | OMEGA-CYCLOHEXYLALKAN-1-OLES AND USE THEREOF AS ANTIMICROBIAL ACTIVES TO COMBAT BODY ODOR | SYMRISE GMBH & CO. KG (DE) | 2009-08-20 | — | — | WO | disclosed |
| WO-2009087242-A2 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | SYMRISE GMBH & CO. KG (DE) | 2009-07-16 | — | — | WO | disclosed |
| WO-2008119841-A2 | COMPOSITIONS COMPRISING BENZYL ALCOHOL DERIVATIVES AND FURTHER ANTIMICROBIAL ACTIVE COMPOUNDS | SYMRISE GMBH & CO. KG (DE) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11801210-B2 | Retinol replacement in skin treatment | RBP1, RBP4, LRAT | CES2 1372/4885CES1 149/4885AKR1C1 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.