Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826355 | 0.75 | TDP1 (0.34) | ALDH1A1KDM4ETSHR | |
| SCHEMBL11202722 | 0.75 | IDO1 (0.38) | — | |
| SCHEMBL3825796 | 0.72 | MEN1 (0.31) | KMT2AMEN1KDM4ETSHR | |
| SCHEMBL9180692 | 0.72 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL9182082 | 0.71 | TSHR (0.30) | TSHR | |
| SCHEMBL8818182 | 0.71 | ALDH1A1 (0.41) | ALDH1A1HTTKMT2AMEN1CYP1A2 | |
| SCHEMBL9181769 | 0.71 | LMNA (0.36) | ALDH1A1HPGD | |
| SCHEMBL29367470 | 0.67 | KMT2A (0.74) | ALDH1A1HTTKMT2AMEN1CYP1A2 | |
| SCHEMBL6524461 | 0.67 | KMT2A (0.74) | ALDH1A1HTTKMT2AMEN1CYP1A2 | |
| SCHEMBL4267841 | 0.67 | KMT2A (0.48) | ALDH1A1HTTKMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0091130-A2 | Cephalosporin derivatives, process for preparing and pharmaceutical compositions containing said compounds | DAIICHI SEIYAKU CO., LTD. (JP) | 1983-10-12 | — | — | EP | disclosed |