SCHEMBL623429

SCHEMBL623429

CCCCn1c(O)cc(C)c(C#N)c1=O

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.60
USP2 O75604 1/20 0.60
LMNA P02545 3/20 0.55
KMT2A Q03164 7/20 0.54
MEN1 O00255 6/20 0.54
MAPT P10636 4/20 0.54
HPGD P15428 1/20 0.47
THRB P10828 1/20 0.44
HSD17B10 Q99714 3/20 0.44
ALDH1A1 P00352 4/20 0.43
MAPK1 P28482 1/20 0.43
TSHR P16473 1/20 0.43
RAB9A P51151 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
GAA P10253 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
UPP1 Q16831 1/20 0.41
GRM2 Q14416 1/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11129423 0.95 KDM4E (0.59) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL8561106 0.94 KDM4E (0.57) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL10887425 0.94 KDM4E (0.57) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL8125127 0.94 KDM4E (0.57) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL10889819 0.94 KDM4E (0.57) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL11208611 0.94 KDM4E (0.57) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL10769714 0.92 KDM4E (0.57) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL10766144 0.92 KDM4E (0.57) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL6136816 0.90 KDM4E (0.73) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL10768477 0.90 KDM4E (0.56) KDM4EUSP2LMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative L'OREAL S.A. 2007-06-14 US claimed
US-7204857-B1 Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL S.A. (FR) 2007-04-17 US claimed
EP-1434552-A1 METHOD FOR DYEING KERATINOUS FIBRES Henkel Kommanditgesellschaft auf Aktien (DE) 2004-07-07 EP claimed
WO-2003030841-A1 METHOD FOR DYEING KERATINOUS FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
JP-61066756-A None JP disclosed
WO-2025063626-A1 INFRARED-TRANSMISSIVE PHOTOSENSITIVE RESIN COMPOSITION, INFRARED-TRANSMISSIVE PIXEL, COLOR FILTER ARRAY, IMAGE SENSOR, AND LIDAR SENSOR 동우 화인켐 주식회사 2025-03-27 WO disclosed
WO-2025063731-A1 COLORED PHOTOSENSITIVE RESIN COMPOSITION, AND COLOR FILTER AND IMAGE DISPLAY DEVICE MANUFACTURED USING SAME 동우 화인켐 주식회사 2025-03-27 WO disclosed
CN-119264697-A Azo dye, colored curable resin composition, color filter, display device, solid-state imaging element, and method for producing azo dye 住友化学株式会社 2025-01-07 CN disclosed
US-20230367049-A1 COLORED COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-11-16 US disclosed
CN-116643456-A Colored curable resin composition, color filter manufactured by using the same, and display device 东友精细化工有限公司 2023-08-25 CN disclosed
EP-4219631-A1 COLORING COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-08-02 EP disclosed
CN-116234878-A Coloring composition 住友化学株式会社 2023-06-06 CN disclosed
US-4225492-A Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines CASSELLA AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
EP-0010165-A1 Process for the preparation of 6-hydroxypyrid-2-ones CASSELLA Aktiengesellschaft (DE) 1980-04-30 EP disclosed
US-4182886-A OPTICAL FILTERS IN COLOR PHOTOGRAPHY CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-01-08 US disclosed
US-4144231-A Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component CASSELLA AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed
US-4143033-A WATER-SOLUBLE DISAZO DYESTUFFS CONTAINING A 2-PHENYL-BENZIMIDAZOLYL,-BENZOXAZOLYL OR-BENZTHIAZOLYL MIDDLE COMPONENT CASSELLA AKTIENGESELLSCHAFT (DE) 1979-03-06 US disclosed
US-4137228-A HIGH TINCTORIAL STRENGTH, COLORFASTNESS CASSELLA AKTIENGESELLSCHAFT (DE) 1979-01-30 US disclosed
US-4097475-A FOR POLYESTERS AND BLENDS WITH CELLULOSE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-06-27 US disclosed
US-4083849-A Process for preparation of 5-cyanopyrid-6-ones BASF AKTIENGESELLSCHAFT (DT) 1978-04-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative KRT18, NDUFB5, NDUFB7 KDM4E 440/4885USP2 3861/4885LMNA 459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.