Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | USP10 | Q14694 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199382 | 0.96 | MAPT (0.34) | MAPTALDH1A1LMNACA1CA2 | |
| SCHEMBL11202097 | 0.94 | MAPT (0.34) | MAPTALDH1A1LMNACA1CA2 | |
| SCHEMBL11208301 | 0.85 | MAPT (0.33) | MAPTALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL10947220 | 0.81 | MEN1 (0.41) | MAPTALDH1A1LMNACYP3A4TSHR | |
| SCHEMBL10949091 | 0.80 | MEN1 (0.42) | MAPTALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL10952797 | 0.79 | MEN1 (0.41) | MAPTALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL11199866 | 0.79 | MAPT (0.33) | MAPTALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL10947216 | 0.79 | PDE7A (0.48) | MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL10949685 | 0.77 | MEN1 (0.54) | MAPTALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL11204589 | 0.76 | MAPT (0.35) | MAPTALDH1A1LMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078536-A2 | Phosphinates and phosphonates and their use in the control of weeds | SANDOZ AG (CH) | 1983-05-11 | — | — | EP | disclosed |