Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | PPOX | P50336 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202097 | 0.86 | MAPT (0.34) | MAPTALDH1A1LMNATDP1MEN1 | |
| SCHEMBL11208301 | 0.83 | MAPT (0.33) | MAPTALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL11205867 | 0.81 | ALDH1A1 (0.34) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL11411623 | 0.81 | MEN1 (0.38) | MAPTALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL11288556 | 0.81 | MAPT (0.34) | MAPTALDH1A1LMNAHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10854582 | 0.80 | MAPT (0.33) | MAPTALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL9860998 | 0.80 | RAB9A (0.33) | MAPTALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL11200433 | 0.79 | MAPT (0.35) | MAPTALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL10855395 | 0.79 | TDP1 (0.32) | MAPTALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL11388198 | 0.79 | TDP1 (0.36) | MAPTALDH1A1LMNAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078536-A2 | Phosphinates and phosphonates and their use in the control of weeds | SANDOZ AG (CH) | 1983-05-11 | — | — | EP | disclosed |