Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | USP10 | Q14694 | 1/20 | 0.30 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202097 | 0.91 | MAPT (0.34) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11200433 | 0.85 | MAPT (0.35) | MAPTALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL11199866 | 0.83 | MAPT (0.33) | MAPTALDH1A1LMNAHPGDCYP1A2 | |
| SCHEMBL11199382 | 0.83 | MAPT (0.34) | MAPTALDH1A1LMNA | |
| SCHEMBL10944300 | 0.80 | MEN1 (0.52) | MAPTALDH1A1LMNACYP1A2CYP2C19 | |
| SCHEMBL9860998 | 0.79 | RAB9A (0.33) | MAPTALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL10877259 | 0.78 | ALDH1A1 (0.42) | MAPTALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL11204589 | 0.77 | MAPT (0.35) | MAPTALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL11205867 | 0.76 | ALDH1A1 (0.34) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11293232 | 0.76 | ALDH1A1 (0.33) | MAPTALDH1A1LMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078536-A2 | Phosphinates and phosphonates and their use in the control of weeds | SANDOZ AG (CH) | 1983-05-11 | — | — | EP | disclosed |