Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199508 | 0.85 | CD274 (0.65) | PDCD1CD274HTR1ADRD2NR1H2 | |
| SCHEMBL11212391 | 0.83 | PDCD1 (0.47) | PDCD1CD274NPC1RAB9APTGS1 | |
| SCHEMBL9342239 | 0.83 | PDCD1 (0.47) | PDCD1CD274PTGS1 | |
| SCHEMBL28006147 | 0.80 | PDCD1 (0.44) | PDCD1CD274NPC1RAB9AL3MBTL1 | |
| SCHEMBL8679942 | 0.80 | PDCD1 (0.44) | PDCD1CD274NR1H3PTGS1 | |
| SCHEMBL8679266 | 0.79 | CD274 (0.50) | PDCD1CD274L3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL5153010 | 0.77 | FFAR4 (0.53) | PDCD1CD274TDP1MAPK1PTGS1 | |
| SCHEMBL9792869 | 0.77 | PDCD1 (0.54) | PDCD1CD274L3MBTL1MAPK1PTGS1 | |
| Ammonia Solution, Strong SCHEMBL9346396 | 0.76 | CD274 (0.47) | PDCD1CD274MAPK1PTGS1 | |
| Ammonia Solution, Strong SCHEMBL2967636 | 0.76 | CD274 (0.47) | PDCD1CD274PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4371726-A | Composition suitable for mechanical power transmission and process for operating traction drives | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 1983-02-01 | — | — | US | disclosed |