Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL9346396

Cc1c(CBr)ccc(-c2ccccc2)c1C.N

nearest known ligand 0.47

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 8/20 0.47
PDCD1 Q15116 6/20 0.47
PTGS1 P23219 1/20 0.37
ESR2 Q92731 1/20 0.36
PARP10 Q53GL7 1/20 0.36
PARP11 Q9NR21 1/20 0.36
DPP4 P27487 1/20 0.35
ALDH1A1 P00352 2/20 0.34
MAPK1 P28482 1/20 0.34
CYP2A6 P11509 1/20 0.34
CYP2B6 P20813 1/20 0.34
TRPA1 O75762 1/20 0.33
TSHR P16473 1/20 0.33
ERBB2 P04626 1/20 0.33
AKT1 P31749 1/20 0.32
AKT2 P31751 1/20 0.32
SQOR Q9Y6N5 1/20 0.32
VSIR Q9H7M9 1/20 0.32
ALOX5 P09917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4151221 0.82 CD274 (0.69) CD274PDCD1PTGS1DPP4ALDH1A1
Ammonia Solution, Strong SCHEMBL2967636 0.81 CD274 (0.47) CD274PDCD1PTGS1ESR2PARP10
SCHEMBL8679266 0.80 CD274 (0.50) CD274PDCD1PTGS1ESR2PARP10
SCHEMBL8679274 0.79 CD274 (0.46) CD274PDCD1PTGS1ESR2PARP10
SCHEMBL9792869 0.78 PDCD1 (0.54) CD274PDCD1PTGS1ESR2PARP10
SCHEMBL4380373 0.78 FOLH1 (0.45) CD274PDCD1PTGS1ESR2TSHR
SCHEMBL11212391 0.77 PDCD1 (0.47) CD274PDCD1PTGS1ALOX5
SCHEMBL9342239 0.77 PDCD1 (0.47) CD274PDCD1PTGS1ESR2PARP10
SCHEMBL11200440 0.76 PDCD1 (0.46) CD274PDCD1PTGS1MAPK1
Ammonia Solution, Strong SCHEMBL6847510 0.74 DPP4 (0.36) CD274PDCD1DPP4ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5008345-A Two-Part Curing System Containing A Metallic Acid Salt And An Ammonium Or Phosphonium Quaternary Salt ZEON CHEMICAL USA, INC. (US) 1991-04-16 US claimed
EP-0362459-B1 Polyacrylate polymers utilizing substituted urea retarder ZEON CHEMICALS USA INC (US) 1994-08-10 EP disclosed
US-5081194-A Quaternary ammonium or phosphonium curing agent ZEON CHEMICALS U.S.A., INC. (US) 1992-01-14 US disclosed
US-5079304-A Curable ZEON CHEMICALS U.S.A., INC. (US) 1992-01-07 US disclosed
US-5008345-A Two-Part Curing System Containing A Metallic Acid Salt And An Ammonium Or Phosphonium Quaternary Salt ZEON CHEMICAL USA, INC. (US) 1991-04-16 US disclosed
EP-0362459-A1 Polyacrylate polymers utilizing substituted urea retarder Zeon Chemicals USA, Inc. (US) 1990-04-11 EP disclosed
EP-0309794-A2 No-post-cure method of curing polyacrylate polymers Zeon Chemicals USA, Inc. (US) 1989-04-05 EP disclosed