Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203798 | 0.86 | ALDH1A1 (0.52) | TSHRALDH1A1TP53 | |
| SCHEMBL10545589 | 0.77 | TSHR (0.50) | TSHRALDH1A1TP53 | |
| SCHEMBL11152825 | 0.76 | TSHR (0.48) | TSHRALDH1A1TP53 | |
| SCHEMBL3075248 | 0.76 | — | — | |
| SCHEMBL3800217 | 0.74 | — | — | |
| SCHEMBL11148347 | 0.70 | TSHR (0.42) | TSHRALDH1A1TP53 | |
| SCHEMBL9676853 | 0.67 | TSHR (0.59) | TSHRALDH1A1TP53 | |
| SCHEMBL11491111 | 0.67 | — | — | |
| SCHEMBL17002612 | 0.67 | TSHR (0.44) | TSHRALDH1A1TP53 | |
| SCHEMBL3798799 | 0.67 | ALDH1A1 (0.52) | TSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013818-B1 | ORGANOSILICON COMPOUNDS, THEIR PREPARATION AND ANTI-TUMOR AGENTS CONTAINING THE SAME | Shin-Etsu Chemical Co., Ltd. (JP) | 1983-04-06 | — | — | EP | disclosed |
| US-4328216-A | W-TRIORGANOSILYL-SUBSTITUTED LINEAR ALKANOIC ACID ANILIDE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1982-05-04 | — | — | US | disclosed |
| EP-0013818-A1 | Organosilicon compounds, their preparation and anti-tumor agents containing the same | Shin-Etsu Chemical Co., Ltd. (JP) | 1980-08-06 | — | — | EP | disclosed |