⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205937 | 0.83 | ALDH1A1 (0.52) | — | |
| SCHEMBL11152825 | 0.82 | TSHR (0.48) | — | |
| SCHEMBL3800217 | 0.80 | — | — | |
| SCHEMBL10791818 | 0.79 | TSHR (0.56) | — | |
| SCHEMBL11200459 | 0.76 | TSHR (0.48) | — | |
| SCHEMBL9066514 | 0.76 | ALDH1A1 (0.50) | — | |
| SCHEMBL11148347 | 0.76 | TSHR (0.42) | — | |
| SCHEMBL445043 | 0.73 | — | — | |
| SCHEMBL6914208 | 0.73 | — | — | |
| SCHEMBL11491111 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12109213-B2 | Fused heterotricyclic organic compounds, pharmaceutical compositions, and medical uses thereof | ALEVERE MEDICAL CORPORATION (US) | 2024-10-08 | — | — | US | disclosed |
| US-20220378795-A1 | FUSED HETEROTRICYCLIC ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ALEVERE MEDICAL CORPORATION | 2022-12-01 | — | — | US | disclosed |
| CN-114008024-A | Compounds having iron death inducing activity and methods of using the same | 费罗治疗公司 | 2022-02-01 | — | — | CN | disclosed |
| EP-1592738-B1 | RESIN COMPOSITIONS | CIBA HOLDING INC (CH) | 2020-07-29 | — | — | EP | disclosed |
| US-7790793-B2 | Amide nucleating agent compositions | CIBA SPECIALTY CHEM. CORP. (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | CANNIZZARO CARINA | 2009-10-01 | — | — | US | disclosed |
| US-20090227543-A1 | PHOSPHONATE COMPOUNDS HAVING IMMUNO-MODULATORY ACTIVITY | CANNIZZARO CARINA | 2009-09-10 | — | — | US | disclosed |
| US-7470724-B2 | Phosphonate compounds having immuno-modulatory activity | GILEAD SCIENCES, INC. (US) | 2008-12-30 | — | — | US | disclosed |
| US-7432261-B2 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-7390916-B2 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | L'OREAL (FR) | 2008-06-24 | — | — | US | disclosed |
| WO-1998040357-A2 | HIV PROTEASE INHIBITORS | AGOURON PHARMACEUTICALS, INC. (US) | 1998-09-17 | — | — | WO | disclosed |
| US-5750568-A | DITERPENE PHORBOIDS | PROCYON PHARMACEUTICALS, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5716968-A | ANTIINFLAMMATORY AGENTS; VIRICIDE | PROCYON PHARMACEUTICALS, INC. (US) | 1998-02-10 | — | — | US | disclosed |
| US-5643948-A | ANTIINFLAMMATORY, ANTICANCER | PROCYON PHARMACEUTICALS, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5502054-A | LARVACIDES FOR INSECTS SUCH AS TOBACCO BUDWORM | FMC CORPORATION (US) | 1996-03-26 | — | — | US | disclosed |
| EP-0553107-A1 | PROTEIN KINASE C MODULATORS WITH ANTI-INFLAMMATORY AND ANTIVIRAL ACTIVITY | PROCYON PHARMACEUTICALS, INC. (US) | 1993-08-04 | — | — | EP | disclosed |
| WO-1992002484-A1 | PROTEIN KINASE C MODULATORS WITH ANTI-INFLAMMATORY AND ANTIVIRAL ACTIVITY | ALDER RESEARCH CENTER LIMITED PARTNERSHIP (US) | 1992-02-20 | — | — | WO | disclosed |
| EP-0013818-B1 | ORGANOSILICON COMPOUNDS, THEIR PREPARATION AND ANTI-TUMOR AGENTS CONTAINING THE SAME | Shin-Etsu Chemical Co., Ltd. (JP) | 1983-04-06 | — | — | EP | disclosed |
| US-4328216-A | W-TRIORGANOSILYL-SUBSTITUTED LINEAR ALKANOIC ACID ANILIDE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1982-05-04 | — | — | US | disclosed |
| EP-0013818-A1 | Organosilicon compounds, their preparation and anti-tumor agents containing the same | Shin-Etsu Chemical Co., Ltd. (JP) | 1980-08-06 | — | — | EP | disclosed |