Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10833244 | 0.89 | F2 (0.42) | SRCGAAF2F10PRSS1 | |
| SCHEMBL13818416 | 0.84 | SRC (0.44) | SRCGAAF2F10PRSS1 | |
| SCHEMBL7428585 | 0.83 | CASP1 (0.43) | SRCGAAF2F10PRSS1 | |
| SCHEMBL12494278 | 0.82 | F2 (0.48) | SRCGAAF2F10PRSS1 | |
| SCHEMBL17770856 | 0.82 | F2 (0.48) | SRCGAAF2F10PRSS1 | |
| SCHEMBL5903395 | 0.81 | SRC (0.42) | SRCGAAF2F10PRSS1 | |
| SCHEMBL13818390 | 0.78 | SRC (0.54) | SRCCASP1CASP8 | |
| SCHEMBL13818394 | 0.77 | SRC (0.49) | SRCF2F10PRSS1CASP1 | |
| SCHEMBL13818397 | 0.76 | SRC (0.46) | SRCCASP1CASP8 | |
| SCHEMBL10833418 | 0.75 | F2 (0.46) | SRCGAAF2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068173-A1 | Perhydro-1,4-thiazepin-5-one and perhydro-1,4-thiazocin-5-one derivatives, process for preparing and pharmceutical composition containing the same | MERCK & CO. INC. (US) | 1983-01-05 | — | — | EP | disclosed |