Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GRN | P28799 | 2/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1120000 | 0.90 | KDM4E (0.33) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL1120194 | 0.80 | KDM4E (0.38) | KLKB1ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL2796935 | 0.79 | MAPT (0.39) | KLKB1ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL15484996 | 0.78 | KDM4E (0.46) | ALDH1A1CYP3A4KDM4EHPGDLMNA | |
| SCHEMBL1119997 | 0.76 | GRN (0.39) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL14487490 | 0.73 | CRACR2A (0.44) | POLB | |
| SCHEMBL1120262 | 0.71 | KDM4E (0.36) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL1120112 | 0.71 | GRN (0.37) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL14487840 | 0.70 | IDH1 (0.39) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL15491636 | 0.69 | LMNA (0.45) | ALDH1A1HSD17B10CYP3A4KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280965-A1 | THIAZOL-4-CARBOXYLIC ACID ESTERS AND THIOESTERS AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-02-09 | — | — | EP | disclosed |
| WO-2009132785-A1 | THIAZOL-4-CARBOXYLIC ACID ESTERS AND THIOESTERS AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2009-11-05 | — | — | WO | disclosed |