Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 5/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1120262 | 0.89 | KDM4E (0.36) | GRNSORT1KDM4EALDH1A1MAPK1 | |
| SCHEMBL1119997 | 0.89 | GRN (0.39) | GRNSORT1KDM4EALDH1A1MAPK1 | |
| SCHEMBL1120194 | 0.85 | KDM4E (0.38) | KDM4EALDH1A1MAPK1HPGDSMN1; SMN2 | |
| SCHEMBL2796935 | 0.81 | MAPT (0.39) | KDM4EALDH1A1MAPK1HPGDSMN1; SMN2 | |
| SCHEMBL1120000 | 0.74 | KDM4E (0.33) | GRNSORT1KDM4EALDH1A1MAPK1 | |
| SCHEMBL15484996 | 0.74 | KDM4E (0.46) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL1120058 | 0.73 | GRN (0.42) | GRNSORT1KDM4EALDH1A1MAPK1 | |
| SCHEMBL1120063 | 0.71 | KLKB1 (0.36) | GRNSORT1KDM4EALDH1A1MAPK1 | |
| SCHEMBL15446682 | 0.70 | GRN (0.39) | GRNSORT1KDM4EALDH1A1MAPK1 | |
| SCHEMBL1120080 | 0.70 | KDM4E (0.37) | KDM4EALDH1A1MAPK1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150237859-A1 | Thiazol-4-Carboxylic Acid Esters and Thioesters as Plant Protection Agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-27 | — | — | US | disclosed |
| EP-2280965-B1 | THIAZOL-4-CARBOXYLIC ACID ESTERS AND THIOESTERS AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2012-08-29 | — | — | EP | disclosed |
| US-20110105429-A1 | Thiazole-4-Carboxylic Acid Esters and Thioesters as Plant Protection Agents | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | US | disclosed |
| EP-2280965-A1 | THIAZOL-4-CARBOXYLIC ACID ESTERS AND THIOESTERS AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-02-09 | — | — | EP | disclosed |
| WO-2009132785-A1 | THIAZOL-4-CARBOXYLIC ACID ESTERS AND THIOESTERS AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2009-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105429-A1 | Thiazole-4-Carboxylic Acid Esters and Thioesters as Plant Protection Agents | ACOT7, LYPLA1, PPT1 | GRN 4288/4885SORT1 2035/4885KDM4E 1123/4885 |
| US-20150237859-A1 | Thiazol-4-Carboxylic Acid Esters and Thioesters as Plant Protection Agents | LYPLA1, ACOT7, PPT1 | GRN 4224/4885SORT1 2052/4885KDM4E 1527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.