Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL376107 | 0.91 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4TSHRKMT2A | |
| SCHEMBL377359 | 0.89 | MAPT (0.42) | ALDH1A1TDP1CYP3A4TSHRKMT2A | |
| SCHEMBL11128553 | 0.87 | MAPT (0.45) | ALDH1A1TDP1CYP3A4TSHRKMT2A | |
| SCHEMBL11215385 | 0.84 | GAA (0.51) | ALDH1A1CYP3A4KMT2AMAPTMEN1 | |
| SCHEMBL4063903 | 0.83 | ALDH1A1 (0.61) | ALDH1A1TDP1CYP3A4TSHRKMT2A | |
| SCHEMBL29650091 | 0.83 | ALDH1A1 (0.61) | ALDH1A1TDP1CYP3A4TSHRKMT2A | |
| SCHEMBL27929922 | 0.83 | PDK1 (0.52) | ALDH1A1TDP1CYP3A4TSHRKMT2A | |
| SCHEMBL28218587 | 0.82 | ALDH1A1 (0.59) | ALDH1A1TDP1CYP3A4TSHRKMT2A | |
| SCHEMBL14798355 | 0.81 | ALDH1A1 (0.60) | ALDH1A1TDP1CYP3A4TSHRKMT2A | |
| SCHEMBL12993689 | 0.81 | MAPT (0.54) | ALDH1A1KMT2AMAPTMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090777-A1 | Disazo pigments, methods for their preparation and their use | CIBA-GEIGY AG (CH) | 1983-10-05 | — | — | EP | disclosed |
| EP-0088726-A1 | Monoazo pigments, methods for their preparation and their use | CIBA-GEIGY AG (CH) | 1983-09-14 | — | — | EP | disclosed |