Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208529 | 0.96 | HDAC3 (0.43) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL11207729 | 0.87 | MAPT (0.47) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL7359104 | 0.85 | MAPT (0.48) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL11208706 | 0.85 | MAPT (0.48) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL11205253 | 0.84 | PPARA (0.38) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL11209543 | 0.82 | MAPT (0.45) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL10436374 | 0.82 | ABCB11 (0.59) | PPARAABCB11LMNAMAPTMAPK1 | |
| SCHEMBL10436378 | 0.82 | ABCB11 (0.59) | PPARAABCB11LMNAMAPTMAPK1 | |
| SCHEMBL10436501 | 0.82 | ABCB11 (0.59) | PPARAABCB11LMNAMAPTMAPK1 | |
| SCHEMBL7432087 | 0.82 | ABCB11 (0.59) | PPARAABCB11LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025192-B1 | SUBSTITUTED OXIRANE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-05-11 | — | — | EP | claimed |
| EP-0025192-A2 | Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-18 | — | — | EP | claimed |