SCHEMBL11200658

SCHEMBL11200658

COc1ccc(N[C@H](C(=O)O)C(C)C)c(OC)c1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
MAPT P10636 2/20 0.52
GAA P10253 1/20 0.51
LPAR1 Q92633 2/20 0.50
CYP1A2 P05177 2/20 0.50
CYP1A1 P04798 1/20 0.50
CYP1B1 Q16678 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
TAS1R3 Q7RTX0 1/20 0.49
TAS1R1 Q7RTX1 1/20 0.49
HPGD P15428 2/20 0.49
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11062219 1.00 ALDH1A1 (0.54) ALDH1A1MAPTGAALPAR1CYP1A2
SCHEMBL11060198 0.87 ALDH1A1 (0.52) ALDH1A1MAPTGAALPAR1CYP1A2
SCHEMBL11197992 0.84 MEN1 (0.46) ALDH1A1MAPTGAACYP1A2MEN1
SCHEMBL11196564 0.84 MMP9 (0.45) ALDH1A1MAPTCYP1A2MEN1KMT2A
SCHEMBL11197997 0.84 MEN1 (0.46) ALDH1A1MAPTGAACYP1A2MEN1
SCHEMBL11196566 0.84 MMP9 (0.45) ALDH1A1MAPTCYP1A2MEN1KMT2A
SCHEMBL11204130 0.80 KMT2A (0.50) ALDH1A1GAALPAR1CYP1A2MEN1
SCHEMBL11059118 0.80 KMT2A (0.50) ALDH1A1GAALPAR1CYP1A2MEN1
SCHEMBL11132085 0.79 ALDH1A1 (0.54) ALDH1A1MAPTGAALPAR1CYP1A2
SCHEMBL5292685 0.77 ALDH1A1 (0.56) ALDH1A1MAPTGAALPAR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4411912-A Insecticidal isovaleric acid esters ZOECON CORPORATION (US) 1983-10-25 US disclosed
US-4243819-A Substituted amino acids ZOECON CORPORATION (US) 1981-01-06 US disclosed