Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.57 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200448 | 0.79 | ESR1 (0.60) | ESR1YTHDC1XDHPDE2AELANE | |
| SCHEMBL2535846 | 0.78 | ESR1 (0.48) | ESR1LMNAPOLBGAAPKM | |
| SCHEMBL8399554 | 0.78 | ESR1 (0.48) | ESR1LMNAPOLBGAAPKM | |
| SCHEMBL30414063 | 0.75 | ESR1 (0.46) | ESR1LMNAPOLBGAAPKM | |
| SCHEMBL25235219 | 0.72 | ESR1 (0.44) | ESR1ELANE | |
| SCHEMBL19933189 | 0.72 | YTHDC1 (0.44) | ESR1YTHDC1XDHPDE2A | |
| SCHEMBL11200114 | 0.69 | PRKCI (0.46) | — | |
| SCHEMBL25234484 | 0.69 | ESR1 (0.44) | ESR1 | |
| Hydrochloric Acid SCHEMBL11197387 | 0.68 | PRKCI (0.45) | — | |
| SCHEMBL5333421 | 0.67 | ESR1 (0.38) | ESR1LMNAPOLBGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |