Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.60 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200698 | 0.79 | ESR1 (0.57) | ESR1ELANEXDHYTHDC1PDE2A | |
| SCHEMBL11202279 | 0.78 | ESR1 (0.49) | ESR1ELANE | |
| SCHEMBL11204580 | 0.66 | PRKCI (0.41) | ESR1XDHYTHDC1PDE2A | |
| SCHEMBL16293255 | 0.64 | ESR1 (0.38) | ESR1ELANE | |
| SCHEMBL28087461 | 0.64 | ESR1 (0.43) | ESR1ELANE | |
| SCHEMBL24175045 | 0.64 | YTHDC1 (0.46) | XDHYTHDC1PDE2A | |
| SCHEMBL14968875 | 0.64 | MAPT (0.49) | ESR1ELANE | |
| SCHEMBL11203602 | 0.64 | PDE2A (0.42) | ELANEXDHYTHDC1PDE2A | |
| SCHEMBL11197439 | 0.60 | PRKCI (0.40) | ESR1ELANEXDHYTHDC1PDE2A | |
| SCHEMBL7681092 | 0.60 | ESR1 (0.34) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |