Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11198472 | 0.98 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNAALOX15USP2 | |
| SCHEMBL11201180 | 0.97 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNAALOX15USP2 | |
| Hydrochloric Acid SCHEMBL11200060 | 0.97 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNAALOX15USP2 | |
| SCHEMBL11207162 | 0.87 | KDM4E (0.55) | ALDH1A1KDM4ELMNAALOX15USP2 | |
| SCHEMBL11203562 | 0.85 | ALDH1A1 (0.63) | ALDH1A1KDM4ELMNAALOX15USP2 | |
| SCHEMBL11204214 | 0.84 | KDM4E (0.53) | ALDH1A1KDM4ELMNAALOX15USP2 | |
| SCHEMBL11197698 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAALOX15USP2 | |
| SCHEMBL11200556 | 0.84 | HTR2C (0.53) | ALDH1A1KDM4EPRKCZHTR2CDRD2 | |
| Hydrochloric Acid SCHEMBL11203600 | 0.84 | ALDH1A1 (0.62) | ALDH1A1KDM4ELMNAALOX15USP2 | |
| SCHEMBL11206910 | 0.83 | KDM4E (0.52) | ALDH1A1KDM4ELMNAALOX15USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |