Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.48 |
| ▸ | ITGAL | P20701 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1436075 | 0.83 | CYP2D6 (0.50) | IDO1CCR2CYP3A4TSHRSLC6A4 | |
| SCHEMBL11206840 | 0.82 | ALDH1A1 (0.47) | ITGB2ICAM1ITGALIDO1CCR2 | |
| SCHEMBL18793099 | 0.78 | ITGB2 (0.47) | ITGB2ICAM1ITGALIDO1CCR2 | |
| SCHEMBL11841338 | 0.77 | ITGB2 (0.46) | ITGB2ICAM1ITGALIDO1AR | |
| SCHEMBL11539625 | 0.77 | ITGB2 (0.46) | ITGB2ICAM1ITGALIDO1AR | |
| SCHEMBL5576227 | 0.77 | CYP1A2 (0.50) | CYP3A4TSHRCYP1A2CYP2C9MAPK1 | |
| SCHEMBL6609114 | 0.76 | SMN1; SMN2 (0.53) | ITGB2ICAM1ITGALARMRGPRX4 | |
| SCHEMBL11210385 | 0.73 | AR (0.49) | ITGB2ICAM1ITGALARMRGPRX4 | |
| SCHEMBL5044607 | 0.73 | ITGB2 (0.55) | ITGB2ICAM1ITGALIDO1CYP3A4 | |
| SCHEMBL3165346 | 0.72 | ITGB2 (0.72) | ITGB2ICAM1ITGALIDO1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4394520-A | SKIN DISORDERS | SOCIETE ANONYME DITE: L'OREAL (FR) | 1983-07-19 | — | — | US | disclosed |
| US-4204064-A | FOR TREATMENT OF SKIN OR SCALP | L'OREAL (FR) | 1980-05-20 | — | — | US | disclosed |
| US-4151301-A | ANTISECRETORY | L'OREAL (FR) | 1979-04-24 | — | — | US | disclosed |
| US-4085217-A | DERIVATIVES OF CYSTEINE OR CYSTEAMINE | L'OREAL (FR) | 1978-04-18 | — | — | US | disclosed |
| US-4002671-A | REDUCE SEBUM SECRETION ON SCALP OR SKIN | SOCIETE ANONYME DITE: L'OREAL (FR) | 1977-01-11 | — | — | US | disclosed |
| US-3976781-A | SULFUR CONTAINING AMINES | L'OREAL (FR) | 1976-08-24 | — | — | US | disclosed |