Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753726 | 0.86 | LMNA (0.45) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| Acetic Acid Methyl Ester SCHEMBL926276 | 0.82 | GAA (0.46) | RAB9ASMN1; SMN2LMNANPC1GAA | |
| SCHEMBL11028082 | 0.82 | PNMT (0.44) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10144132 | 0.78 | PTGS2 (0.47) | RAB9ASMN1; SMN2LMNANPC1GAA | |
| SCHEMBL7058662 | 0.77 | MEN1 (0.56) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2655184 | 0.77 | DHFR (0.41) | RAB9ASMN1; SMN2LMNANPC1GAA | |
| SCHEMBL1436075 | 0.77 | CYP2D6 (0.50) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7247115 | 0.77 | SOD1 (0.40) | RAB9ASMN1; SMN2LMNANPC1PRMT1 | |
| SCHEMBL11200775 | 0.77 | ITGB2 (0.48) | CYP1A2CYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL10986918 | 0.77 | LMNA (0.45) | RAB9ASMN1; SMN2LMNANPC1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742918-A1 | LXR RECEPTOR MODULATORS | LABORATOIRES FOURNIER S.A. (FR) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005121093-A1 | LXR RECEPTOR MODULATORS | LABORATOIRES FOURNIER S.A. (FR) | 2005-12-22 | — | — | WO | disclosed |