Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10974516 | 0.88 | PTGS2 (0.41) | PTGS2PTGS1TSHRLMNACYP2C9 | |
| SCHEMBL10981665 | 0.85 | L3MBTL1 (0.43) | PTGS2PTGS1TSHRALDH1A1LMNA | |
| SCHEMBL10979187 | 0.82 | PTGS2 (0.45) | PTGS2PTGS1TSHRALDH1A1LMNA | |
| SCHEMBL10974081 | 0.82 | PTGS2 (0.44) | PTGS2PTGS1TSHRLMNACYP2C9 | |
| SCHEMBL11064897 | 0.80 | CXCR1 (0.43) | PTGS2PTGS1TSHRLMNACYP2C9 | |
| SCHEMBL11201051 | 0.79 | PTGS2 (0.40) | PTGS2PTGS1TSHRLMNACYP2C9 | |
| SCHEMBL10974786 | 0.77 | PTGS2 (0.38) | PTGS2PTGS1TSHRLMNACYP2C9 | |
| SCHEMBL15896744 | 0.77 | KDM4E (0.49) | PTGS2PTGS1TSHRALDH1A1LMNA | |
| SCHEMBL15897196 | 0.77 | KDM4E (0.49) | PTGS2PTGS1TSHRALDH1A1LMNA | |
| SCHEMBL11064345 | 0.77 | APP (0.41) | PTGS2PTGS1TSHRLMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4420631-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1983-12-13 | — | — | US | disclosed |