SCHEMBL11201170

SCHEMBL11201170

O=C(O)COC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.53
TP53 P04637 1/20 0.52
TSHR P16473 1/20 0.52
KDM4E B2RXH2 3/20 0.50
ALDH1A1 P00352 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
GAA P10253 1/20 0.50
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
HPGD P15428 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.47
SRD5A2 P31213 1/20 0.46
LMNA P02545 2/20 0.46
MAPK1 P28482 2/20 0.46
TDP1 Q9NUW8 2/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA3 P07451 1/20 0.44
TYR P14679 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11201167 0.93 KDM4E (0.55) MAPTKDM4EALDH1A1L3MBTL1GAA
SCHEMBL831507 0.85 LMNA (0.62) MAPTTSHRKDM4EALDH1A1NPC1
SCHEMBL582352 0.84 TDP1 (0.63) TSHRKDM4EALDH1A1L3MBTL1GAA
SCHEMBL20656251 0.83 RAB9A (0.69) MAPTTP53KDM4EALDH1A1L3MBTL1
SCHEMBL9127865 0.83 LMNA (0.55) MAPTKDM4EALDH1A1L3MBTL1GAA
Potassium SCHEMBL31360984 0.83 TDP1 (0.61) TSHRKDM4EALDH1A1L3MBTL1GAA
SCHEMBL27502116 0.83 TDP1 (0.61) TSHRKDM4EALDH1A1L3MBTL1GAA
SCHEMBL28819015 0.83 TDP1 (0.61) TSHRKDM4EALDH1A1L3MBTL1GAA
SCHEMBL22418 0.82 TDP1 (0.59) MAPTTP53TSHRALDH1A1NPC1
SCHEMBL1081433 0.82 TSHR (0.57) MAPTTP53TSHRALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117343295-A Preparation method of biodegradable copolyester based on terephthalic acid and ethylene glycol ester 浙江恒逸石化研究院有限公司 2024-01-05 CN disclosed
US-4390683-A Stretched film structure of the poly-1,3-phenylene terephthalate type MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1983-06-28 US disclosed
EP-0052927-A2 Stretched film structure of the poly-1,3-phenylene terephthalate type MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-06-02 EP disclosed