Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.42 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.42 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.42 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.42 |
| ▸ | CBFB | Q13951 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9110481 | 0.81 | CYP1A2 (0.47) | ALDH1A1MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL9110493 | 0.81 | HTT (0.47) | ALDH1A1MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL18622117 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL3981200 | 0.79 | KMT2A (0.45) | ALDH1A1MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL28165041 | 0.78 | ALDH1A1 (0.52) | ALDH1A1RAB9AKDM4ESMN1; SMN2CYP2C19 | |
| SCHEMBL4094348 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL7771746 | 0.74 | TSHR (0.59) | ALDH1A1MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL13414534 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL11639262 | 0.73 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL1443707 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |