Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202244 | 0.86 | MAPT (0.47) | PTPN11SMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL11133041 | 0.84 | HCRTR1 (0.51) | PTPN11GBA1HCRTR1HCRTR2PIK3CA | |
| SCHEMBL11206583 | 0.82 | PTPN11 (0.41) | PTPN11GBA1HCRTR1HCRTR2PIK3CA | |
| SCHEMBL11201993 | 0.82 | HCRTR1 (0.37) | HCRTR1HCRTR2ITGB2ICAM1ITGAL | |
| SCHEMBL11204218 | 0.81 | KDM4E (0.41) | HCRTR1HCRTR2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11198496 | 0.80 | KDM4E (0.40) | HCRTR1HCRTR2SMN1; SMN2 | |
| SCHEMBL11205242 | 0.71 | MAPT (0.45) | PTPN11SMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL11206086 | 0.70 | HCRTR1 (0.51) | PTPN11GBA1HCRTR1HCRTR2PIK3CA | |
| SCHEMBL11202336 | 0.70 | MAPK1 (0.51) | NPSR1MEN1KMT2A | |
| SCHEMBL11202238 | 0.70 | GBA1 (0.39) | PTPN11GBA1PIK3CASMN1; SMN2CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |