Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR7 | P34969 | 3/20 | 0.31 |
| ▸ | HTR6 | P50406 | 3/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197939 | 0.84 | HCRTR1 (0.49) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| SCHEMBL11201229 | 0.82 | PTPN11 (0.40) | HCRTR1HCRTR2ITGB2ICAM1ITGAL | |
| SCHEMBL11202902 | 0.82 | HCRTR1 (0.38) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| SCHEMBL11204218 | 0.81 | KDM4E (0.41) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| SCHEMBL11202884 | 0.81 | HCRTR1 (0.47) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11198496 | 0.81 | KDM4E (0.40) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| SCHEMBL11201413 | 0.79 | HCRTR1 (0.36) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| SCHEMBL11201137 | 0.79 | ESR1 (0.39) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL11203490 | 0.79 | ELANE (0.36) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL11202244 | 0.78 | MAPT (0.47) | KDM4EALDH1A1MAPTMAPK1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |