Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11201229 | 0.86 | PTPN11 (0.40) | KMT2AMEN1PTPN11SMN1; SMN2NPSR1 | |
| SCHEMBL11205242 | 0.86 | MAPT (0.45) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL11201993 | 0.78 | HCRTR1 (0.37) | MAPTKMT2AALDH1A1MAPK1ELANE | |
| SCHEMBL11204218 | 0.76 | KDM4E (0.41) | MAPTALDH1A1HPGDSMN1; SMN2TSHR | |
| SCHEMBL11201579 | 0.76 | MEN1 (0.50) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11198496 | 0.75 | KDM4E (0.40) | MAPTALDH1A1HPGDSMN1; SMN2TSHR | |
| SCHEMBL11201436 | 0.74 | MAPT (0.45) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL11206583 | 0.73 | PTPN11 (0.41) | KMT2AMEN1ALDH1A1PTPN11SMN1; SMN2 | |
| SCHEMBL11133041 | 0.73 | HCRTR1 (0.51) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL11204710 | 0.73 | ACACA (0.68) | MAPTKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |