Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.45 |
| ▸ | KCNB2 | Q92953 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | F2R | P25116 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202803 | 0.85 | CA12 (0.49) | KMT2AALDH1A1KDM4EGLACA12 | |
| SCHEMBL11205210 | 0.83 | HDAC1 (0.48) | KMT2AALDH1A1KDM4EGLACA12 | |
| SCHEMBL11206589 | 0.75 | KMT2A (0.50) | KMT2AALDH1A1GLAMEN1MAPT | |
| SCHEMBL18880072 | 0.72 | ALDH1A1 (0.73) | KMT2AALDH1A1KDM4EGLACA12 | |
| SCHEMBL21367673 | 0.70 | SMN1; SMN2 (0.58) | KMT2AALDH1A1MEN1F2RMAPT | |
| SCHEMBL13390684 | 0.70 | KDM4C (0.57) | KMT2AALDH1A1KDM4EGLACA12 | |
| SCHEMBL13883703 | 0.69 | KMT2A (0.54) | KMT2AALDH1A1KDM4EGLACA12 | |
| SCHEMBL9430771 | 0.69 | KDM4E (0.57) | KMT2AALDH1A1KDM4EGLAMEN1 | |
| SCHEMBL29793403 | 0.69 | KCNB1 (0.59) | KCNB1MAPT | |
| SCHEMBL9313903 | 0.68 | KMT2A (0.57) | KMT2AALDH1A1KDM4EGLACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4409232-A | HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1983-10-11 | — | — | US | disclosed |