Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.45 |
| ▸ | KCNB2 | Q92953 | 1/20 | 0.45 |
| ▸ | F2R | P25116 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11201281 | 0.85 | KMT2A (0.48) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL13390684 | 0.83 | KDM4C (0.57) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL11204834 | 0.83 | POLB (0.54) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL9313903 | 0.79 | KMT2A (0.57) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL11202032 | 0.78 | KMT2A (0.66) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL7553405 | 0.76 | KMT2A (0.61) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL15678237 | 0.76 | KMT2A (0.54) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL11284272 | 0.75 | KMT2A (0.50) | KMT2AMAPTALDH1A1GLAMEN1 | |
| SCHEMBL11214314 | 0.74 | HDAC3 (0.57) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL13009075 | 0.74 | KMT2A (0.53) | CA12CA1CA2CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045955-B1 | ALKYL AND CYCLOALKYL SUBSTITUTED 2-(2-(2-HYDROXY-3-TERT.-BUTYLAMINO-PROPOXY)-5-ACYLAMINOPHENYL)-1,3,4-OXADIAZOLES, THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | Beiersdorf Aktiengesellschaft (DE) | 1983-08-31 | — | — | EP | disclosed |
| EP-0045955-A1 | Alkyl and cycloalkyl substituted 2-(2-(2-hydroxy-3-tert.-butylamino-propoxy)-5-acylaminophenyl)-1,3,4-oxadiazoles, their preparation and pharmaceutical preparations containing them | Beiersdorf Aktiengesellschaft (DE) | 1982-02-17 | — | — | EP | disclosed |